Lancet Oncology Commission on Medical Imaging and Nuclear Medicine Launched at ECR 2021

The first comprehensive effort to quantify imaging and nuclear medicine resources worldwide, highlighting dramatic inequalities in access to these resources, was launched at the European Congress of Radiology 2021. The Lancet Oncology Commission on Medical Imaging and Nuclear Medicine demonstrated that scaling up access to imaging and nuclear medicine for cancer patients in low-income and middle-income countries (LMICs) would yield substantial health and economic benefits, and it calls for an overarching global strategy to address this need.

"The aim of the Commission was to provide data and guidance to catalyze sustainable improvement of medical imaging and nuclear medicine services for cancer management, particularly in LMICs," explains lead Commissioner Dr. Hedvig Hricak from Memorial Sloan Kettering Cancer Center, New York/USA.

Worldwide, annual numbers of new cancer cases and cancer deaths are expected to reach roughly 22 million and 13 million, respectively, by 2030. Approximately 80% of the disability-adjusted life years lost to cancer are in LMICs, where only about 5% of the global funding for cancer control and care is applied. Imaging is essential to provide timely diagnosis, appropriate treatment selection and planning, and optimal outcomes for patients with cancer.

A microsimulation model developed by researchers at Harvard University estimated that the scale-up of imaging would avert 3.2% (2.47 million) of all 76 million deaths caused by cancer worldwide between 2020 and 2030, saving 54.92 million life-years. Model estimates indicate that a comprehensive scale-up of imaging, treatment, and care quality would avert 9.55 million (12.5%) of all cancer deaths worldwide, saving 232.30 million life-years. Combining the scale-up of imaging, treatment, and quality of care would provide a net bene􀀁t of $2.66 trillion and a net return of $12.43 per $1 invested.

Under the Commission, the International Atomic Energy Agency (IAEA) led a global effort to collect and collate data on equipment and workforce, with a focus on LMICs through the IAEA Medical Imaging and Nuclear Medicine Global Resources Database (IMAGINE). The effort revealed substantial differences in the numbers of imaging units per million population between high-income and low- and middle-income countries, as well as variations within income groups. It also revealed that availability of a well-trained workforce for imaging and nuclear medicine is a major issue affecting access to and quality of these services.

"To date, comprehensive information on appropriate levels of imaging and nuclear medicine facilities and workforce required for cancer care have been limited. The data obtained allows estimates of projected equipment and workforce scale-up requirements for diagnostic imaging in cancer care," says Dr. May Abdel-Wahab, co-first author of the Commission and Director of the IAEA Division of Human Health.

"For the first time, we have evidence demonstrating the substantial health and economic benefits of scaling up imaging and nuclear medicine access for health outcomes of cancer patients globally and we have a compelling economic case for further investment in global scale-up of imaging and nuclear medicine," says Dr. Rifat Atun, co-first author of the Commission and Professor of Global Health Systems at Harvard University.

The Commission proposes an ambitious call to action to realize the health and economic benefits of scaling up imaging to reduce cancer burden globally. This goal is aligned with the aims of the 2017 WHO Cancer Resolution and with UN health targets in the 2030 agenda for sustainable development, particularly for reducing the burden of non-communicable diseases and implementing universal health coverage.

The Commission concludes that science and technology are not the barriers to a worldwide equitable scale-up of effective cancer imaging diagnostics; rather, achieving equitable scale-up is a matter of vision and political will. Successful scale-up will result from effective political leadership, active participation from all major stakeholders, and the alignment of country-level and global efforts to expand access to medical imaging and nuclear medicine for cancer care. Efforts must take into account local and regional conditions (e.g., the prevalence of particular cancers and the availability of specific kinds of treatments, among other factors), and must be coordinated with the scale-up of other cancer care resources and universal health coverage. Prof David Collingridge, Editor-in-Chief, The Lancet Oncology: "Cancer imaging is vital for accurate diagnosis and treatment, but huge global inequities exist and many of the world's poorest countries suffer from a shortage or complete lack of the necessary technology and resources. We need to move the debate so that cancer imaging is placed alongside curative interventions as an essential component of comprehensive cancer care, and in turn, universal health coverage."

Read the Commission at www.thelancet.com/commissions/medical-imaging-nuclear-medicine