Black Patients Have Longer Wait for Uterine Cancer Testing, Diagnosis

A new analysis by Yale researchers published in the Journal of the National Cancer Institute provides insights into why black patients are less likely to receive early diagnoses than people of other racial and ethnic groups. They found that black patients were more likely than their white counterparts to experience testing delays or to not receive recommended tests at all.

“Early diagnosis is important,” said Xiao Xu, PhD, MA, an associate professor of obstetrics, gynecology, and reproductive sciences at Yale School of Medicine, member of Yale Cancer Center, and lead author of the study. “We don’t know why there’s a racial disparity in early diagnosis and until we do, it’s hard to address it.”

To determine whether differences in the diagnosis process contribute to this disparity, Dr Xu and her colleagues used the MarketScan Multi-State Medicaid Database, which has deidentified data from more than 44 million Medicaid patients across the United States.

For their analysis, they included adult patients who had reported abnormal uterine bleeding to their health care providers and later received a diagnosis of uterine cancer. Abnormal uterine bleeding is the most common symptom of uterine cancer, Dr Xu said, and can present as light spotting or heavier bleeding at unexpected times.

The American College of Obstetricians and Gynecologists recommends several procedures to evaluate the cause of abnormal uterine bleeding, such as endometrial biopsy, transvaginal/pelvic ultrasound, and hysteroscopy, in which a physician examines the inside of the cervix and uterus with a small, telescope-like device. In the new study, researchers found that more than twice as many black patients than white patients did not receive any of these procedures (10.1% of black patients versus 5% of white patients).

Further, of the patients who did receive procedures, black patients were more likely than white patients to experience a delay of more than two months in receiving their first diagnostic procedure following their report of abnormal uterine bleeding.

Ultimately, black patients were more likely than white patients to experience a delay in receiving their cancer diagnosis. The researchers found that 11.3% of black patients who’d reported abnormal uterine bleeding waited more than a year to receive a uterine cancer diagnosis, compared with 8.3% of white patients.

“Overall, we found a pretty consistent difference in the quality of care received by black and white patients,” said Dr Xu.

To better understand the driving factors behind this difference in care and how best to address them, Dr Xu and her colleagues are evaluating additional sets of data to determine whether black patients might experience barriers to accessing specialist care, if more education about the symptoms of uterine cancer may be beneficial for patients, and whether delays in diagnoses result in patients being diagnosed at later stages of cancer. They are also studying whether these findings among Medicaid patients are similarly seen in other patient populations.

“The goal,” said Dr Xu, “is for every patient to receive high-quality care.”